Finding the right medication to treat your depression can be difficult. You may have to try several different medications before you find the right one for you. The more you know about your options for medication, the easier it will be for you and your doctor to find the right treatment.

Celexa and Lexapro are popular drugs used to treat depression. Here’s a comparison of the two to help you as you discuss options with your doctor.

Drug Features
Both Celexa and Lexapro belong to a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs). Serotonin is a substance in your brain that helps control your mood. These medications work by increasing serotonin levels to help treat symptoms of depression.

Principle of Action
Being the representatives of the same group of medications, Celexa and Lexapro use similar methods to beat their mutual opponents: depression, anxiety or both. These medications work in human brains by preventing the reabsorption of serotonin, which is one of the neurotransmitters (chemicals, delivering signals from one brain cell to another). As the result, the amount of serotonin increases, and this is believed to have positive effect on relieving the symptoms of depression or anxiety.

Dosage
Celexa is available as 10, 20, and 40mg coated tablets or as a liquid solution taken orally. Your doctor will likely prescribe a 20 mg dose of citalopram, taken once a day, to start. That dose could be increased gradually to 40 mg a day as you adjust to the medication. It can be taken with or without food. It is very important that Celexa pills be swallowed whole and not chewed, broken, or crushed.
Lexapro comes in tablet form, in 5, 10 or 20mg. It also comes in liquid form. Generally, the effective dose of Lexapro ranges from 10 to 20 mg daily. People usually take Lexapro once a day, either in the morning or at night, with or without food. It is very important that Lexapro pills be swallowed whole and not chewed, broken, or crushed.

Safety
Evaluating safety profiles of Celexa and Lexapro is not an easy task; however, it is far more difficult to define the safer medication among these two antidepressants. The most common side effects are nausea, insomnia, problems with ejaculation, drowsiness and fatigue. The same adverse reactions have been identified in association with both Celexa and Lexapro. However, some statistic data says that people on Lexapro have approximately the same chances to experience side effects as people, taking sugar pills. On the other hand, Celexa may sometimes cause tremor, dry mouth and diarrhea, - reactions, that are not typical for Lexapro. So, Lexapro seems to be more convincing during this round too.

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